Funded by Welsh Government via the Health and Care Research Wales infrastructure, the Brain Repair and Intracranial Neurotherapeutics (BRAIN) is a research unit developing novel therapeutics and treatment delivery systems for neurological conditions.
BRAIN operates under the directorship of Professor William Gray with 31 principle investigators and collaborators, with a total grant income of over £34 million since its inception in 2015.
It is our vision that the Brain Repair and Intracranial Neurotherapeutics (BRAIN) unit will be a Welsh and UK national centre of excellence, and on a path towards international leadership for:
- Delivering novel cell/gene/small molecules and other pioneering complex therapies to human brain.
- Supporting translational research underpinning disease modification and brain repair in patients with neurological conditions.
Our aims for the next three years are:
- To develop new and refine existing systems for therapeutics delivery into the human brain
- Develop appropriate infrastructure for:
- Developing adult and fetal brain tissue resources, supporting translational research and therapy validation across neurological diseases
- Bio-banking and bio-resource management using linked and deeply phenotyped clinical data
- Consolidate and extend appropriate clinical trials and expertise, including refinement of appropriate methodologies for evaluating novel complex interventions
- Embed into all BRAIN work, cross-cutting excellence in the relation to:
- Public and Patient Involvement & Engagement
- Industry and NHS Engagement and Collaboration