As we move away from the challenges of COVID we have been able to harness the benefits of online tools and reimagine our involvement and engagement delivery. In this article, we shine a light on some of the PPI activities from 2022 - 23. Our…
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BRAIN successfully delivers the UniQure Phase I/II gene therapy trial in Huntington’s Disease
We are delighted to have successfully delivered the UniQure Phase I/II gene therapy trial focussing on knocking down Huntington protein production within neurons in Huntington’s Disease, to three patients in Cardiff. This gene therapy is potentially curative or significantly slowing disease progression in this fatal…
SEE MOREMeet the researcher: Susruta Manivanan
As a Clinical Research Fellow in Neurosurgery, Susruta is working on identifying strategies for optimising the effective delivery of cell and gene-therapies to the brain, under the supervision of Professor Liam Gray. About me I am a neurosurgical trainee currently taking time out of…
SEE MORELEARN study webinar reveals experiences of participants on neurosurgical trials
Participants, funders and principal investigators came together to discuss the key findings of a recent Cardiff University study, and to present resources that people with Parkinson's disease and their support partners can use when considering research participation. The LEARN study stands for 'listening to the…
SEE MOREAll fun and BRAIN games: Looking back on May
May 2023 was a busy month for the BRAIN Unit, from science talks science to hosting the highly anticipated BRAIN games, with primary school attendees from across Cardiff. Read on to find out more. Science with a pint: hearts and minds research On May…
SEE MOREGame-changing technology: £1m grant will enable BRAIN Unit researchers discover brain abnormalities that cause disease
Researchers at Cardiff University have been awarded funding that will enable them to better map the brain to treat diseases such as epilepsy, dementia, and multiple sclerosis. A £1 million grant from the Medical Research Council was secured by Cardiff University, along with University College…
SEE MOREMeet the researcher: Dr Benjamin Dummer
Dr Benjamin Dummer is a Research Assistant based in a lab at the University Hospital of Wales (UHW), under the supervision of Professor Liam Gray. The research Our current research focuses on glioblastoma, which is a deadly brain cancer. We are characterising a 3D cell…
SEE MOREHow far have we come with cell and gene therapies?
BRAIN researchers have co-edited a book which examines the progress of cell therapies in the treatment of neurodegenerative diseases, published last November. Cell therapies are a promising development for the treatment of neurodegenerative diseases (NDDs) such as Huntington’s and Parkinson’s, which occur when nerve cells…
SEE MOREMeet the Researcher: Lauren Griffiths
Lauren Griffiths is a Research Technician at Swansea University. Her recent research has centred around cholesterol, its function in the brain, and understanding its role in neurodegenerative diseases. Cholesterol is an essential molecule in the body, and especially in the brain, where it is the…
SEE MOREWhat you may not know about Parkinson’s disease
Around 145,000 people live with Parkinson’s in the UK, and it's the fastest-growing neurological condition in the world. For World Parkinson's Day, Dr Emma Lane from the BRAIN Unit discusses the disease and some things you may not know. What is Parkinson's disease? Parkinson's disease…
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