{"id":3766,"date":"2022-03-25T16:48:17","date_gmt":"2022-03-25T16:48:17","guid":{"rendered":"https:\/\/brain.wales\/2022\/03\/epilepsi-datblygu-cohortau-syn-barod-ar-gyfer-ymchwil\/"},"modified":"2026-04-10T14:13:00","modified_gmt":"2026-04-10T13:13:00","slug":"epilepsi-datblygu-cohortau-syn-barod-ar-gyfer-ymchwil","status":"publish","type":"post","link":"https:\/\/brain.wales\/cy\/2022\/03\/epilepsi-datblygu-cohortau-syn-barod-ar-gyfer-ymchwil\/","title":{"rendered":"Epilepsi: datblygu cohortau sy’n barod ar gyfer ymchwil"},"content":{"rendered":"

Yn y wobr 2018-20, derbyniodd Uned BRAIN gyllid i ddatblygu system Cofnod Cleifion Electronig (EPR) sy’n cefnogi gofal clinigol a ffenoteipio cleifion dwfn mewn Sglerosis Ymledol (Caerdydd a’r Fro ac Aneurin Bevan), Clefyd Parkinson (Abertawe Bro-Morgannwg) ac Epilepsi (Caerdydd a’r Fro).<\/p>\n

Mae’r system yn cael ei defnyddio trwy weinydd diogel sy’n wynebu’r rhyngrwyd y tu \u00f4l i wal d\u00e2n y GIG<\/a> , gan ganiat\u00e1u i ymchwilwyr gydweithio’n ddiogel a chyfrannu setiau data ar lefel cleifion. Tua diwedd y dyfarniad, defnyddiwyd modiwl amlddisgyblaethol newydd ar gyfer y rhaglen llawdriniaeth epilepsi (Caerdydd a’r Fro). Mae cronfa ddata PatientCare bellach wedi’i hintegreiddio’n dda ac mae ganddi ddefnydd trawsddisgyblaethol, gan wella gofal cleifion.<\/p>\n

Datblygu’r system EPR<\/h2>\n

Rydym nawr yn dymuno ehangu ar y platfform hwn i ddatblygu cohortau sy’n barod ar gyfer ymchwil, lle cynhelir data ffenoteip diagnostig a chlinigol manwl ochr yn ochr \u00e2 chydsyniad cleifion i gael eu cysylltu ar gyfer ymchwil, a lle cesglir a storio biolegol meinweoedd, sef serwm a plasma yn fwyaf cyffredin ar gyfer biomarcwyr genetig a biomarcwyr clefydau eraill.<\/p>\n

Mae rhaglen eisoes ar waith ar gyfer Sglerosis Ymledol i gleifion yn Ne Cymru dan arweiniad yr Athro Neil Robertson, gan ddefnyddio cronfa ddata glinigol ‘PatientCare’ a banc meinweoedd Niwrowyddoniaeth Cymru. Rydym yn datblygu piblinell debyg ar gyfer cleifion ag epilepsi, mae cronfa ddata PatientCare eisoes yn cael ei defnyddio i gasglu data diagnostig a thriniaeth fel rhan o ofal clinigol arferol.<\/p>\n

Bydd cyllid ychwanegol gan yr Uned BRAIN yn mynd tuag at ymestyn y gwaith hwn i gynnig ymchwil ffurfiol gyda chymeradwyaeth Moeseg ac Ymchwil a Datblygu&#39;r GIG ar gyfer casglu data meinwe a data para-glinigol (sef sgan yr ymennydd (MRI) ac electroenseffalograff (EEG)) gyda chydsyniad y claf ar gyfer storio ac ymchwil ymlaen, ar gyfer cleifion ag epilepsi sy&#39;n mynychu clinigol arbenigol ym myrddau iechyd Caerdydd a&#39;r Fro a Chwm Taf.<\/p>\n

Mae hyn yn cefnogi un o brif amcanion a chryfderau BRAIN, sef y cysylltiad dwyffordd agos rhwng ymchwil academaidd a gofal clinigol arferol y GIG, gan roi mynediad i gleifion \u00e2 chyflyrau niwrolegol sy’n mynychu clinigau cleifion allanol i ymchwil glinigol a threialon clinigol.<\/p><\/blockquote>\n

Ehangu’r t\u00eem<\/h2>\n

I gyflawni&#39;r ymchwil hwn, croesawon ni Valerie Anderson i d\u00eem Uned BRAIN, i gefnogi cronfa ddata glinigol epilepsi a sefydlu casgliadau samplau, gan weithio i ddechrau ar y protocol, moeseg a chymeradwyaethau Ymchwil a Datblygu.<\/p>\n

Bydd hyn o fudd i ymchwilwyr eraill mewn epilepsi, a fydd \u00e2 mynediad at y data a’r samplau a gasglwyd, yn creu carfannau sy’n barod ar gyfer ymchwil ar gyfer treialon clinigol ac astudiaethau wrth iddynt ddatblygu, a fyddai ar gael i unrhyw ymchwilwyr Uned BRAIN a chydweithwyr allanol. A bydd yn agor cyfleoedd ar gyfer cydweithio \u00e2 mentrau ymchwil eraill yn y DU ac yn rhyngwladol.<\/p>\n

Sefydlodd Valerie brosiect tebyg yn flaenorol mewn Sglerosis Ymledol. Bydd ei phrofiad a’i gwybodaeth o wneud hyn yn ein galluogi i symud ymlaen ar gyflymder i sefydlu pethau ar gyfer epilepsi, ac yna gweithio ymhellach ar redeg y prosiect ar \u00f4l ei sefydlu.<\/p>\n

Ar \u00f4l ei sefydlu, fel y rhagwelwyd o fewn y cyfnod ariannu 12 mis, byddai recriwtio, caniat\u00e2d, casglu samplau a choladu data yn parhau trwy gyfarfyddiadau clinigol safonol. Byddai data ar gael ar gyfer ymchwil a byddai cyllid dilynol yn cael ei geisio ar gyfer seilwaith a chymorth penodol i brosiectau.<\/p>\n","protected":false},"excerpt":{"rendered":"

Yn y wobr 2018-20, derbyniodd Uned BRAIN gyllid i ddatblygu system Cofnod Cleifion Electronig (EPR) sy’n cefnogi gofal clinigol a ffenoteipio cleifion dwfn mewn Sglerosis Ymledol (Caerdydd a’r Fro ac Aneurin Bevan), Clefyd Parkinson (Abertawe Bro-Morgannwg) ac Epilepsi (Caerdydd a’r Fro). Mae’r system yn cael ei defnyddio trwy weinydd diogel sy’n wynebu’r rhyngrwyd y tu […]<\/p>\n","protected":false},"author":9,"featured_media":3534,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[18],"tags":[17],"class_list":["post-3766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-heb-ei-gategoreiddio","tag-prydain-fawr"],"acf":[],"yoast_head":"\nEpilepsi: datblygu cohortau sy'n barod ar gyfer ymchwil - Ymennydd Cymru<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/brain.wales\/cy\/2022\/03\/epilepsi-datblygu-cohortau-syn-barod-ar-gyfer-ymchwil\/\" \/>\n<meta property=\"og:locale\" content=\"cy_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Epilepsi: datblygu cohortau sy'n barod ar gyfer ymchwil - Ymennydd Cymru\" \/>\n<meta property=\"og:description\" content=\"Yn y wobr 2018-20, derbyniodd Uned BRAIN gyllid i ddatblygu system Cofnod Cleifion Electronig (EPR) sy’n cefnogi gofal clinigol a ffenoteipio cleifion dwfn mewn Sglerosis Ymledol (Caerdydd a’r Fro ac Aneurin Bevan), Clefyd Parkinson (Abertawe Bro-Morgannwg) ac Epilepsi (Caerdydd a’r Fro). 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